Transmission dynamics of Q fever in French Guiana: A population-based cross-sectional study.

ABSTRACT:

Background

Q fever is a zoonosis caused by Coxiella burnetii which is among the major agents of community-acquired pneumonia in French Guiana. Despite its relatively high incidence, its epidemiology in French Guiana remains unclear, and all previous studies have considered transmission from livestock unlikely, suggesting that a wild reservoir is responsible for transmission.

Methods

A country-wide seroprevalence survey of 2697 participants from French Guiana was conducted. Serum samples were tested for phase II IgG antibodies by ELISA and indirect immunofluorescence assays (IFAs). Factors associated with Q fever were investigated, and a serocatalytic model was used to reconstruct the annual force of infection.

Findings

The overall weighted seroprevalence was es

SUBMITTER: Bailly S 

PROVIDER: S-EPMC9903881 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature