Haff Disease in Salvador, Brazil, 2016-2021: Attack rate and detection of toxin in fish samples collected during outbreaks and disease surveillance.

ABSTRACT:

Background

From late 2016 to early 2021, cases of Haff disease, a rare cause of rhabdomyolysis, possibly due to poisoning by palytoxin-like compounds in seafood, were detected in Salvador, Brazil. Surveillance was established to detect additional cases aiming at describing the clinical characteristics of the cases, identifying associated factors, estimating disease attack rate, and investigating the presence of biotoxins and trace metals in selected fish specimens obtained from cases.

Method

Between December/2016-January/2021, surveillance investigated Haff disease suspected cases, and obtained clinical and fish samples to test.

Findings

Of 65 cases investigated during the 2016-2017 outbreak, 43 (66%) had high creatine phosphokinase (CPK) levels. Among those with labo

SUBMITTER: Cardoso CW 

PROVIDER: S-EPMC9904022 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature