Rates of Circumpapillary Retinal Nerve Fiber Layer Thinning and Capillary Density Loss in Glaucomatous Eyes with Disc Hemorrhage.

ABSTRACT:

Purpose

To investigate longitudinal changes in rates of optic nerve head circumpapillary retinal nerve fiber layer (cpRNFL) thinning and vessel density loss in patients with primary open-angle glaucoma with or without a history of disc hemorrhage (DH).

Design

Observational cohort.

Methods

In this longitudinal study, 34 eyes with DH and 134 eyes without DH that had ≥1.5 years of follow-up and 3 optical coherence tomography and optical coherence tomography angiography follow-up scans were enrolled. A linear mixed-effects model was used to compare the rates of cpRNFL thinning and vessel density loss between DH and non-DH eyes.

Results

Rates of whole image capillary density loss were faster in the DH group compared with the non-DH group (mean difference [95% confid

SUBMITTER: Nishida T 

PROVIDER: S-EPMC9904188 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature