Antibiotic resistance and mecA characterization of Staphylococcus hominis from filarial lymphedema patients in the Ahanta West District, Ghana: A cross-sectional study.

ABSTRACT:

Background and aim

Filarial infections affect over 150 million people in the tropics. One of the major forms of filarial pathologies is lymphedema; a condition where the immune response is significantly altered, resulting in changes in the normal flora. Staphylococcus hominis, a human skin commensal, can also be pathogenic in immunocompromised individuals. Therefore, there is the possibility that S. hominis could assume a different behavior in filarial lymphedema patients. To this end, we investigated the levels of antibiotic resistance and extent of mecA gene carriage in S. hominis among individuals presenting with filarial lymphedema in rural Ghana.

Method

We recruited 160 individuals with stages I-VII lymphedema, in a cross-sectional study in t

SUBMITTER: Kini P 

PROVIDER: S-EPMC9904197 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature