Time spent with HIV-RNA ≤ 200 copies/ml in a cohort of people with HIV during the U=U era.

ABSTRACT:

Objective

Zero risk of linked HIV transmission in serodiscordant couples when the HIV-infected partner had viral load less than 200 copies/ml ('U status') was found in observational studies. We aimed at estimating the proportion of time in which 'U status' was maintained and identifying factors associated with the risk of losing it.

Design

Observational cohort study.

Methods

We included participants in the ICONA cohort who had reached an established 'U status' (viral load ≤200 copies/ml for >6 months) as of December 2010. The outcome was the number of person-days of follow-up (PDFU) above a viral load greater than 200 copies/ml, relative to the total number of PDFU observed. A logistic regression model was used to identify factors independently associated with the ris

SUBMITTER: Madeddu G 

PROVIDER: S-EPMC9904439 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature