Resuscitation in the First 3 Hours of Sepsis-Induced Hypotension Varies by Patient and Hospital Factors.

ABSTRACT: Patient and hospital factors affects how we resuscitate patients in the first 3 hours of sepsis-induced hypotension.

Objectives

To evaluate variability in compliance to the 3-hour surviving sepsis campaign (SSC) bundle and explore the association of early compliance with subsequent shock and in-hospital mortality.

Design

Retrospective cohort study between September 2017 and February 2018.

Setting

Thirty-four academic medical centers.

Participants

A subgroup sepsis-induced hypotensive patients from a larger shock cohort study.

Main outcomes and measures

Compliance to SSC bundle that was defined as receiving appropriate antibiotics, 30 mL/kg of crystalloid or initiation of vasopressors, and lactate, obtained in the first 3 hours following sepsis-induced hyp

SUBMITTER: Chen JT 

PROVIDER: S-EPMC9904767 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature