Poor Prognostic Biomarker KIAA1522 Is Associated with Immune Infiltrates in Hepatocellular Carcinoma.

ABSTRACT:

Background

The prognosis is poor for hepatocellular carcinoma (HCC), a tumor and cancer associated with inflammation that is common. New data showed that significant levels of KIAA1522 were expressed in HCC tissues and cell lines, suggesting that KIAA1522 may be a highly useful prognostic marker for HCC. However, its biochemical processes and impacts on the immune system go deeper.

Objective

To verify the significance of KIAA1522 in HCC and investigate its related carcinogenic mechanisms.

Methods

Studies examining the relationship between KIAA1522 expression and clinical-pathologic characteristics in HCC have been checked in the Cancer Genome Atlas (TCGA) database. A receiver operating characteristic (ROC) curve was used to assess the diagnostic efficacy of KIAA1522 i

SUBMITTER: Shi Y 

PROVIDER: S-EPMC9904920 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature