Interactions between natural products and cancer treatments: underlying mechanisms and clinical importance.

ABSTRACT: Natural products, also referred to as dietary supplements, complementary and alternative medicines, and health or food supplements are widely used by people living with cancer. These products are predominantly self-selected and taken concurrently with cancer treatments with the intention of improving quality of life, immune function and reducing cancer symptoms and treatment side effects. Concerns have been raised that concurrent use may lead to interactions resulting in adverse effects and unintended treatment outcomes. This review provides an overview of the mechanisms by which these interactions can occur and the current evidence about specific clinically important natural product-drug interactions. Clinical studies investigating pharmacokinetic interactions provide evidence that negati

SUBMITTER: Chan WJ 

PROVIDER: S-EPMC9905199 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature