Population-Based Opioid Prescribing and Overdose Deaths in the USA: an Observational Study.

ABSTRACT:

Background

Rising opioid-related death rates have prompted reductions of opioid prescribing, yet limited data exist on population-level associations between opioid prescribing and opioid-related deaths.

Objective

To evaluate population-level associations between five opioid prescribing measures and opioid-related deaths.

Design

An ecological panel analysis was performed using linear regression models with year and commuting zone fixed effects.

Participants

People ≥10 years aggregated into 886 commuting zones, which are geographic regions collectively comprising the entire USA.

Main measures

Annual opioid prescriptions were measured with IQVIA Real World Longitudinal Prescription Data including 76.5% (2009) to 90.0% (2017) of US prescriptions. Prescriptio

SUBMITTER: Olfson M 

PROVIDER: S-EPMC9905341 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature