Ultra-processed food consumption and risk of colorectal cancer precursors: results from 3 prospective cohorts.

ABSTRACT:

Background

Growing evidence indicates the adverse effect of ultra-processed food (UPF) consumption. However, it remains unknown whether UPF consumption influences the risk of colorectal cancer (CRC) precursors, namely conventional adenomas and serrated lesions.

Methods

We drew data from the Nurses' Health Study, Nurses' Health Study II, and Health Professionals Follow-up Study, comprising 142 052 participants who had undergone at least 1 lower gastrointestinal endoscopy during follow-up. To handle multiple records per participants, we used multivariable logistic regression for clustered data to calculate odds ratios (OR) and 95% confidence intervals (CIs) of colorectal polyps in relation to cumulative average consumption of UPFs. All statistical tests were 2-sided.

Result

SUBMITTER: Hang D 

PROVIDER: S-EPMC9905956 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature