Expression and clinical significance of undifferentiated embryonic cell transcription factor 1 in breast cancer.

ABSTRACT:

Background

At present, due to the heterogeneity of breast cancer, common tumor markers have certain limitations in clinical prognostic evaluation. This suggests an unmet need for markers to predict clinical outcomes and potentially guide targeted therapies. The present study sought to explore the expression level and clinical significance of undifferentiated embryonic cell transcription factor 1 (UTF1) in breast cancer.

Methods

Immunohistochemistry (IHC) was used to detect the expression of UTF1 in 221 breast cancer samples. The clinical significance of UTF1 protein expression in breast cancer tissues was evaluated by combining clinicopathological parameters and UTF1 expression profile. We performed 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) and clone

SUBMITTER: Lou Y 

PROVIDER: S-EPMC9906053 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature