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The association of serum folate and homocysteine on venous thromboembolism in patients with colorectal cancer: a cross-sectional study.


ABSTRACT:

Background

Venous thromboembolism is a common complication in patients with colorectal cancer who exhibit high homocysteine and low folate levels. However, whether venous thrombosis is the result of a direct effect of folic acid or the presence of a homocysteine-mediated mediating effect cannot be determined. This study aimed to explore the association and mediating effects of serum folate and homocysteine on venous thromboembolism in patients with colorectal cancer.

Methods

This study included patients with colorectal cancer who were admitted to the First Hospital of Shanxi Medical University from May 2020 to May 2022. The patients' medical records were reviewed to collect information on general demographic characteristics, the prevalence of venous thromboembolism on admiss

SUBMITTER: Cao Y 

PROVIDER: S-EPMC9906060 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature