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Bronchiectasis exacerbation: a narrative review of causes, risk factors, management and prevention.


ABSTRACT:

Background and objective

Bronchiectasis exacerbations are significant events in the natural course of the disease and determine long-term clinical outcomes. This review aims to discuss the definition, causes, risk factors, management and prevention of bronchiectasis exacerbations.

Methods

The PubMed database was searched for relevant articles published in English between January 1990 and March 2022 using keywords "bronchiectasis" and "exacerbation".

Key content and findings

Causes of bronchiectasis exacerbation are multifactorial; it can be associated with bacterial and viral pathogens, host inflammatory responses, and external environmental effects. In addition, recent advances in bronchiectasis research highlight the phenotype of patients who are more prone to exace

SUBMITTER: Choi H 

PROVIDER: S-EPMC9906191 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature