Impact of Membrane Voltage on Formation and Stability of Human Renal Proximal Tubules in Vitro.

ABSTRACT: More than 15% of adults in the United States suffer from some form of chronic kidney disease (CKD). Current strategies for CKD consist of dialysis or kidney transplant, which, however, can take several years. In this light, tissue engineering and regenerative medicine approaches are the key to improving people's living conditions by advancing previous tissue engineering approaches and seeking new targets as intervention methods for kidney repair or replacement. The membrane voltage (V_m) dynamics of a cell have been associated with cell migration, cell cycle progression, differentiation, and pattern formation. Furthermore, bioelectrical stimuli have been used as a means in the treatment of diseases and wound healing. Here, we investigated the role of V_m a

SUBMITTER: Adelfio M 

PROVIDER: S-EPMC9906498 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature