Sarcopenia as a risk factor of progression-free survival in patients with metastases: a systematic review and meta-analysis.

ABSTRACT:

Background

Metastasis of cancer causes more than 90% of cancer deaths and is severely damaging to human health. In recent years, several studies have linked sarcopenia to shorter survival in patients with metastatic cancer. Several predictive models exist to predict mortality in patients with metastatic cancer, but have reported limited accuracy.

Methods

We systematically searched Medline, EMBASE, and the Cochrane Library for articles published on or before October 14, 2022. Pooled Hazard Ratio (HR) estimates with 95% confidence intervals (CIs) were calculated using a random effects model. The primary outcome was an increased risk of death or tumor progression in patients with metastatic cancer, which is expressed as progression-free survival (PFS). In addition, we performed

SUBMITTER: Luo L 

PROVIDER: S-EPMC9906917 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature