Final Report of a Trial of Intensive versus Standard Blood-Pressure Control.

ABSTRACT:

Background

In a previously reported randomized trial of standard and intensive systolic blood-pressure control, data on some outcome events had yet to be adjudicated and post-trial follow-up data had not yet been collected.

Methods

We randomly assigned 9361 participants who were at increased risk for cardiovascular disease but did not have diabetes or previous stroke to adhere to an intensive treatment target (systolic blood pressure, <120 mm Hg) or a standard treatment target (systolic blood pressure, <140 mm Hg). The primary outcome was a composite of myocardial infarction, other acute coronary syndromes, stroke, acute decompensated heart failure, or death from cardiovascular causes. Additional primary outcome events occurring through the end of the intervention period (Au

SUBMITTER: SPRINT Research Group 

PROVIDER: S-EPMC9907774 | biostudies-literature | 2021 May

REPOSITORIES: biostudies-literature