Effects of gene-lifestyle interactions on obesity based on a multi-locus risk score: A cross-sectional analysis.

ABSTRACT:

Background

The relationship between lifestyle and obesity is a major focus of research. Personalized nutrition, which utilizes evidence from nutrigenomics, such as gene-environment interactions, has been attracting attention in recent years. However, evidence for gene-environment interactions that can inform treatment strategies is lacking, despite some reported interactions involving dietary intake or physical activity. Utilizing gene-lifestyle interactions in practice could aid in optimizing interventions according to genetic risk.

Methods

This study aimed to elucidate the effects of gene-lifestyle interactions on body mass index (BMI). Cross-sectional data from the Japan Multi-Institutional Collaborative Cohort Study were used. Interactions between a multi-locus genetic r

SUBMITTER: Nakamura S 

PROVIDER: S-EPMC9907830 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature