Anorexia nervosa and microbiota: systematic review and critical appraisal.

ABSTRACT:

Purpose

Recent studies have reported a gut microbiota imbalance or dysbiosis associated with anorexia nervosa (AN), which has prompted an appraisal of its aetiological role, and the reformulation of AN as a metabo-psychiatric disorder. Thus, the aim of this paper was to critically review the current scientific findings regarding the role of microbiota in anorexia nervosa.

Methods

A systematic study of peer-reviewed literature published in four databases between 2009 and 2022 was conducted according to PRISMA guidelines. Both human and animal studies were included.

Results

A total of 18 studies were included. In animal models, both the preclinical and clinical findings were inconsistent regarding microbiota composition, faecal metabolite concentrations, and the effects

SUBMITTER: Garcia N 

PROVIDER: S-EPMC9908645 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature