Design and implementation of a hybrid cloud system for large-scale human genomic research.

ABSTRACT: In the field of genomic medical research, the amount of large-scale information continues to increase due to advances in measurement technologies, such as high-performance sequencing and spatial omics, as well as the progress made in genomic cohort studies involving more than one million individuals. Therefore, researchers require more computational resources to analyze this information. Here, we introduce a hybrid cloud system consisting of an on-premise supercomputer, science cloud, and public cloud at the Kyoto University Center for Genomic Medicine in Japan as a solution. This system can flexibly handle various heterogeneous computational resource-demanding bioinformatics tools while scaling the computational capacity. In the hybrid cloud system, we demonstrate the way to properly perf

SUBMITTER: Nagasaki M 

PROVIDER: S-EPMC9908893 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature