Physicochemical properties of otic products for Canine Otitis Externa: comparative analysis of marketed products.

ABSTRACT:

Background

Otitis externa is a commonly diagnosed dermatological disorder in canines. The pathogens primarily involved in canine otitis externa (COE) include Staphylococcus pseudintermedius, Pseudomonas aeruginosa, Proteus mirabilis, and Malassezia pachydermatis. As COE tends to be superficial, medications delivered topically are often effective and practical in managing the condition. As such, there is a wide variety of approved topical products currently available in the market. The efficacy of topical dosage forms can be dependent on various factors such as the pharmacology of active constituents and the physicochemical properties of the formulation, including pH, viscosity, spreadability, and bio-adhesion. Currently, there is a lack of published literature available on the opti

SUBMITTER: Song Y 

PROVIDER: S-EPMC9909939 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature