MRI-based radiomics nomogram for differentiation of solitary metastasis and solitary primary tumor in the spine.

ABSTRACT:

Background

Differentiating between solitary spinal metastasis (SSM) and solitary primary spinal tumor (SPST) is essential for treatment decisions and prognosis. The aim of this study was to develop and validate an MRI-based radiomics nomogram for discriminating SSM from SPST.

Methods

One hundred and thirty-five patients with solitary spinal tumors were retrospectively studied and the data set was divided into two groups: a training set (n = 98) and a validation set (n = 37). Demographics and MRI characteristic features were evaluated to build a clinical factors model. Radiomics features were extracted from sagittal T1-weighted and fat-saturated T2-weighted images, and a radiomics signature model was constructed. A radiomics nomogram was established by combining radiomics fea

SUBMITTER: Li S 

PROVIDER: S-EPMC9909949 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature