Effects of SARS-CoV-2 vaccine (Vero cells) on disease activity in patients with inflammatory bowel disease in China: a multicenter study.

ABSTRACT:

Aims

To evaluate the impact of SARS-CoV-2 vaccine on IBD activity.

Methods

Adult IBD patients from five large IBD centers in China were enrolled and followed up for 6 months. Patients were divided into vaccinated and unvaccinated groups according to vaccination status. Demographic and clinical data were collected.

Results

A total of 280 individuals (213 UC and 67 CD patients) were enrolled in the study. The unvaccinated and vaccinated groups of UC patients were comparable for basic characteristics, including age (t = - 0.8, p = 0.425), sex (χ² = 0.980, p = 0.322), course of disease (z = - 0.513, p = 0.608), surgical conditions (χ² = 1.042, p = 0.838), disease extent (χ² = 4.853, p = 0.088), or baseline drug therapy (χ² = 7.7

SUBMITTER: Zhang M 

PROVIDER: S-EPMC9910246 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature