Cerebral Edema in Patients with severe Hemispheric Syndrome: Incidence, Risk Factors, and Outcomes-Data from SITS-ISTR.

ABSTRACT:

Background and purpose

Cerebral edema (CED) in ischemic stroke can worsen prognosis and about 70% of patients who develop severe CED die if treated conservatively. We aimed to describe incidence, risk factors and outcomes of CED in patients with extensive ischemia.

Methods

Oservational study based on Safe Implementation of Treatments in Stroke-International Stroke Treatment Registry (2003-2019). Severe hemispheric syndrome (SHS) at baseline and persistent SHS (pSHS) at 24 hours were defined as National Institutes of Health Stroke Score (NIHSS) >15. Outcomes were moderate/severe CED detected by neuroimaging, functional independence (modified Rankin Scale 0-2) and death at 90 days.

Results

Patients (n=8,560) presented with SHS and developed pSHS at 24 hours; 82.2% recei

SUBMITTER: Escudero-Martinez I 

PROVIDER: S-EPMC9911855 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature