Implications of missing data on reported breast cancer mortality.

ABSTRACT:

Background

National cancer registries are valuable tools to analyze patterns of care and clinical outcomes; yet, missing data may impact the accuracy and generalizability of these data. We sought to evaluate the association between missing data and overall survival (OS).

Methods

Using the NCDB (National Cancer Database) and SEER (Surveillance, Epidemiology, End Results Program), we assessed data missingness among patients diagnosed with invasive breast cancer from 2010 to 2014. Key variables included demographic (age, race, ethnicity, insurance, education, income), tumor (grade, ER, PR, HER2, TNM stages), and treatment (surgery in both databases; chemotherapy and radiation in NCDB). OS was compared between those with and without missing data using Cox proportional hazards mo

SUBMITTER: Plichta JK 

PROVIDER: S-EPMC9912364 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature