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Synthesis, characterization, and crystal structures of N,N'-bis-(2-di-alkyl-amino-phen-yl)thio-ureas.

ABSTRACT: N,N'-Bis[2-(di-methyl-amino)-phen-yl]thio-urea, C₁₇H₂₂N₄S (1), and N,N'-bis-[2-(di-ethyl-amino)-phen-yl]thio-urea, C₂₁H₃₀N₄S (2), were prepared by the treatment of 1,1'-thio-carbonyl-diimidazole and 2 equivalents of 2-amino-N,N'-di-alkyl-aniline. Both compounds exhibit intra-molecular hydrogen bonds between the N-H(thio-urea) and NR ₂ (R = Me, Et) groups. The other N-H bonds face the sulfur atoms of S=C bonds in an adjacent mol-ecule, which forms an inter-molecular inter-action in the packed structure. The structural details match the spectroscopic data acquired from NMR and IR spectroscopy.

SUBMITTER: Lee K

PROVIDER: S-EPMC9912467 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature

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Synthesis, characterization, and crystal structures of N,N'-bis-(2-di-alkyl-amino-phen-yl)thio-ureas.

Lee Kyounghoon K

Acta crystallographica. Section E, Crystallographic communications 20230106 Pt 2

N,N'-Bis[2-(di-methyl-amino)-phen-yl]thio-urea, C17H22N4S (1), and N,N'-bis-[2-(di-ethyl-amino)-phen-yl]thio-urea, C21H30N4S (2), were prepared by the treatment of 1,1'-thio-carbonyl-diimidazole and 2 equivalents of 2-amino-N,N'-di-alkyl-aniline. Both compounds exhibit intra-molecular hydrogen bonds between the N-H(thio-urea) and NR 2 (R = Me, Et) gro ...[more]

PMID: 36793414

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