Syntheses and crystal structures of two di-naph-tho[2,1-d:1',2'-f][1,3]dithiepine atropisomers.

ABSTRACT: The closely related title compounds, 1-(di-naphtho-[2,1-d:1',2'-f][1,3]dithiepin-4-yl)-2,2-di-methyl-propan-1-ol, C₂₆H₂₄OS₂, 1 and 2-(di-naphtho-[2,1-d:1',2'-f][1,3]dithiepin-4-yl)-3,3-di-methyl-butan-2-ol, C₂₇H₂₆OS₂, 2, both comprise an atrop-isomeric binaphthyl di-thio-acetal unit substituted at the methyl-ene carbon atom with a chiral neopentyl alcohol grouping. The overall stereochemistry of the racemate in each case is defined as aS,R and aR,S. In 1, the hydroxyl group generates inversion dimers via pairwise inter-molecular O-H⋯S hydrogen bonds whereas in 2, the O-H⋯S link is intra-molecular. Weak C-H⋯π inter-actions link the mol-ecules into ex

SUBMITTER: Beare N 

PROVIDER: S-EPMC9912471 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature