Neural biomarker diagnosis and prediction to mild cognitive impairment and Alzheimer's disease using EEG technology.

ABSTRACT:

Background

Electroencephalogram (EEG) has emerged as a non-invasive tool to detect the aberrant neuronal activity related to different stages of Alzheimer's disease (AD). However, the effectiveness of EEG in the precise diagnosis and assessment of AD and its preclinical stage, amnestic mild cognitive impairment (MCI), has yet to be fully elucidated. In this study, we aimed to identify key EEG biomarkers that are effective in distinguishing patients at the early stage of AD and monitoring the progression of AD.

Methods

A total of 890 participants, including 189 patients with MCI, 330 patients with AD, 125 patients with other dementias (frontotemporal dementia, dementia with Lewy bodies, and vascular cognitive impairment), and 246 healthy controls (HC) were enrolled. Biomarker

SUBMITTER: Jiao B 

PROVIDER: S-EPMC9912534 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature