Air Pollution and the Risk of Dementia: The Rotterdam Study.

ABSTRACT:

Background

Exposure to air pollution has been suggested to increase the risk of dementia, but studies on this link often lack a detailed screening for dementia and data on important confounders.

Objective

To determine the association of exposure to air pollution with the risk of dementia and cognitive decline in the population-based Rotterdam Study.

Methods

Between 2009 and 2010, we determined air pollutant concentrations at participants residential addresses using land use regression models. Determined air pollutants include particulate matter <10μm (PM10) and <2.5μm (PM2.5), a proxy of elemental carbon (PM2.5 absorbance), nitrogen oxide (NOx), and nitrogen dioxide (NO2). As the individual air pollutant levels were highly correlated (r = 0.71-0.98), we computed a gen

SUBMITTER: de Crom TOE 

PROVIDER: S-EPMC9912721 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature