Hemispheric Patterns of Recruitment of Object Processing Regions in Early Alzheimer's Disease: A Study Along the Entire Ventral Stream.

ABSTRACT:

Background

Investigation of neural response patterns along the entire network of functionally defined object recognition ventral stream regions in Alzheimer's disease (AD) is surprisingly lacking.

Objective

We aimed to investigate putative functional reorganization along a wide-ranging network of known regions in the ventral visual stream in mild AD.

Methods

Overall we investigated 6 regions of interest (5 of which were not investigated before), in 19 AD patients and 19 controls, in both hemispheres along the ventral visual stream: Fusiform Face Area, Fusiform Body Area, Extrastriate Body Area, Lateral Occipital Cortex, Parahippocampal Place Area, and Visual Word Form Area, while assessing object recognition performance.

Results

We found group differences in dp

SUBMITTER: Canario NS 

PROVIDER: S-EPMC9912740 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature