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Management of patients with mitral regurgitation ineligible for standard therapy undergoing TMVI screening.


ABSTRACT:

Background

Transcatheter mitral valve implantation (TMVI) represents a novel treatment alternative for patients with severe mitral regurgitation (MR) considered ineligible for standard therapies. Data on the management of patients after TMVI screening are scarce.

Aims

We aimed to investigate outcomes of patients with severe MR undergoing TMVI evaluation treated with either TMVI, bailout-transcatheter edge-to-edge repair (bailout-TEER) or medical therapy (MT).

Methods

Between May 2016 and February 2021, 121 patients with MR considered ineligible for standard therapy were screened for TMVI. Outcomes were assessed for the subgroups of patients treated with TMVI, bailout-TEER and MT. The primary composite endpoint was all-cause death or heart failure hospitalisation after

SUBMITTER: Ludwig S 

PROVIDER: S-EPMC9912962 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature