Presurgical Executive Functioning in Low-Grade Glioma Patients Cannot Be Topographically Mapped.

ABSTRACT: Executive dysfunctions have a high prevalence in low-grade glioma patients and may be the result of structural disconnections of particular subcortical tracts and/or networks. However, little research has focused on preoperative low-grade glioma patients. The frontotemporoparietal network has been closely linked to executive functions and is substantiated by the superior longitudinal fasciculus. The aim of this study was to investigate their role in executive functions in low-grade glioma patients. Patients from two neurological centers were included with IDH-mutated low-grade gliomas. The sets of preoperative predictors were (i) distance between the tumor and superior longitudinal fasciculus, (ii) structural integrity of the superior longitudinal fasciculus, (iii) overlap between tumor an

SUBMITTER: Landers MJF 

PROVIDER: S-EPMC9913560 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature