Predictors of Remission in Severe Childhood Immune Thrombocytopenia.

ABSTRACT: Childhood immune thrombocytopenia (ITP; platelet count < 100 × 10⁹/L) is the most common bleeding disorder in children. A total of 3-5% of children with ITP face a greater risk of bleeding, resulting in significant morbidity and mortality. Childhood ITP is often benign and self-limited; however, children with severe ITP (platelet count < 30 × 10⁹/L) require investigation and monitoring. In addition, 20% of ITP patients may not go into remission (platelet counts < 100 × 10⁹/L by 12 months after diagnosis) and may develop chronic ITP. The early identifying predictors associated with the resolution of severe ITP at the time of diagnosis may be helpful for family guidance. However, there is still controversy about the associations between the clinical factors a

SUBMITTER: Cheng CN 

PROVIDER: S-EPMC9914323 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature