Chemical Profiles and Toxicity of Electronic Cigarettes: An Umbrella Review and Methodological Considerations.

ABSTRACT:

Background

Electronic cigarettes (ECs) are often marketed as a safer alternative to combustible tobacco products. The global EC market has rapidly expanded since their introduction, creating an urgent need for research describing the toxicity and chemical composition of ECs. We conducted an umbrella review to summarize the evidence from existing systematic reviews (SRs).

Methods

The search for SRs was conducted across four electronic databases through 25 January 2022. Methodological quality was assessed using the AMSTAR-2 quality appraisal tool.

Results

Twenty-five SRs were included in our umbrella review. Chemical profiles widely varied across studies included in the reviews, which was mainly attributed to the lack of standardized protocols investigating the constitu

SUBMITTER: Travis N 

PROVIDER: S-EPMC9914618 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature