Multifunctional ferromagnetic fiber robots for navigation, sensing, and treatment in minimally invasive surgery.

ABSTRACT: Small-scale robots capable of remote active steering and navigation offer great potential for biomedical applications. However, the current design and manufacturing procedure impede their miniaturization and integration of various diagnostic and therapeutic functionalities. Here, we present a robotic fiber platform for integrating navigation, sensing, and therapeutic functions at a submillimeter scale. These fiber robots consist of ferromagnetic, electrical, optical, and microfluidic components, fabricated with a thermal drawing process. Under magnetic actuation, they can navigate through complex and constrained environments, such as artificial vessels and brain phantoms. Moreover, we utilize Langendorff mouse hearts model, glioblastoma microplatforms, and in vivo mouse models to demonstra

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC9915472 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature