Prenatal Sex Hormone Exposure Is Associated with the Development of Autism Spectrum Disorder.

ABSTRACT: Sexual differentiation is a major developmental process. Sex differences resulting from sexual differentiation have attracted the attention of researchers. Unraveling what contributes to and underlies sex differences will provide valuable insights into the development of neurodevelopmental disorders that exhibit sex biases. Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects an individual's social interaction and communication abilities, and its male preponderance has been consistently reported in clinical studies. The etiology of male preponderance remains unclear, but progress has been made in studying prenatal sex hormone exposure. The present review examined studies that focused on the association between prenatal testosterone exposure and ASD development, as w

SUBMITTER: Li M 

PROVIDER: S-EPMC9916422 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature