Antenatal corticosteroid administration-to-birth interval and neonatal outcomes in very preterm infants: A secondary analysis based on a prospective cohort study.

ABSTRACT:

Introduction

Despite the prevalent use of antenatal corticosteroids (ACS) to prevent preterm infants' adverse neonatal complications, there is currently no consensus on administration-to-birth intervals of ACS. International guidelines broadly agree that the administration of antenatal corticosteroids should be within 7 days prior to preterm birth. However, there is little evidence to support narrower optimal ACS administration-to-birth interval time. This study was undertaken to investigate the association between the administration-to-birth interval of ACS which is bounded by 48 hours and neonatal outcomes in very preterm infants.

Materials and methods

This is a single-center prospective observational study. Data were collected prospectively from eligible infants from Janu

SUBMITTER: Wang D 

PROVIDER: S-EPMC9916588 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature