Congenital diaphragmatic hernia in a middle-income country: Persistent high lethality during a 12-year period.

ABSTRACT:

Background

In high- and middle-income countries, mortality associated to congenital diaphragmatic hernia (CDH) is high and variable. In Brazil, data is scarce regarding the prevalence, mortality, and lethality of CDH. This study aimed to analyze, in São Paulo state of Brazil, the temporal trends of prevalence, neonatal mortality and lethality of CDH and identify the time to CDH-associated neonatal death.

Methods

Population-based study of all live births with gestational age ≥ 22 weeks, birthweight ≥400g, from mothers residing in São Paulo State, Brazil, during 2004-2015. CDH definition and its subgroups classification were based on ICD-10 codes reported in the death and/or live birth certificates. CDH-associated neonatal death was defined as death up to 27 days after birth o

SUBMITTER: Scavacini Marinonio AS 

PROVIDER: S-EPMC9916629 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature