SABRE Hyperpolarization with up to 200 bar Parahydrogen in Standard and Quickly Removable Solvents.

ABSTRACT: Parahydrogen (p-H₂)-based techniques are known to drastically enhance NMR signals but are usually limited by p-H₂ supply. This work reports p-H₂-based SABRE hyperpolarization at p-H₂ pressures of hundreds of bar, far beyond the typical ten bar currently reported in the literature. A recently designed high-pressure setup was utilized to compress p-H₂ gas up to 200 bar. The measurements were conducted using a sapphire high-pressure NMR tube and a 43 MHz benchtop NMR spectrometer. In standard methanol solutions, it could be shown that the signal intensities increased with pressure until they eventually reached a plateau. A polarization of about 2%, equal to a molar polarization of 1.2 mmol L^-

SUBMITTER: Duchowny A 

PROVIDER: S-EPMC9917027 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature