Drug-Drug Interactions of Cannabidiol with Standard-of-Care Chemotherapeutics.

ABSTRACT: Cannabidiol (CBD) is an easily accessible and affordable Marijuana (Cannabis sativa L.) plant derivative with an extensive history of medical use spanning thousands of years. Interest in the therapeutic potential of CBD has increased in recent years, including its anti-tumour properties in various cancer models. In addition to the direct anticancer effects of CBD, preclinical research on numerous cannabinoids, including CBD, has highlighted their potential use in: (i) attenuating chemotherapy-induced adverse effects and (ii) enhancing the efficacy of some anticancer drugs. Therefore, CBD is gaining popularity as a supportive therapy during cancer treatment, often in combination with standard-of-care cancer chemotherapeutics. However, CBD is a biologically active substance that modul

SUBMITTER: Buchtova T 

PROVIDER: S-EPMC9917508 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature