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Effects of Glucomannan Supplementation on Type II Diabetes Mellitus in Humans: A Meta-Analysis.


ABSTRACT: The hypoglycemic and lipid-lowering effects of glucomannan are widely known, and it is a potential effective treatment for type II diabetes. In this study, we evaluated the effects of glucomannan supplementation on blood-lipid-related indicators, blood-glucose-related indicators, blood pressure (BP), and body weight (BW) in patients suffering from type II diabetes. We searched databases including PubMed, Cochrane, the comprehensive biomedical research database (Embase), Web of Science, and China National Knowledge Infrastructure (CNKI) for literature on glucomannan and type II diabetes. Six randomized controlled trials (RCTs) were eligible (n = 440 participants) to be included in our analysis. Glucomannan not only reduced the total cholesterol (TC) (MD -0.38 [95% CI: -0.61, -0.15],

SUBMITTER: Zhang Z 

PROVIDER: S-EPMC9919128 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature