A Novel Digital Digit-Symbol Substitution Test Measuring Processing Speed in Adults At Risk for Alzheimer Disease: Validation Study.

ABSTRACT:

Background

Assessing cognitive constructs affected by Alzheimer disease, such as processing speed (PS), is important to screen for potential disease and allow for early detection. Digital PS assessments have been developed to provide widespread, efficient cognitive testing, but all have been validated only based on the correlation between test scores. Best statistical practices dictate that concurrent validity should be assessed for agreement or equivalence rather than using correlation alone.

Objective

This study aimed to assess the concurrent validity of a novel digital PS assessment against a gold-standard measure of PS.

Methods

Adults aged 45-75 years (n=191) participated in this study. Participants completed the novel digital digit-symbol substitution test (DDSST

SUBMITTER: Campitelli A 

PROVIDER: S-EPMC9919459 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature