Photocrosslinked Fish Collagen Peptide/Chitin Nanofiber Composite Hydrogels from Marine Resources: Preparation, Mechanical Properties, and an In Vitro Study.

ABSTRACT: Fish collagen peptide (FCP) is a water-soluble polymer with easy accessibility, bioactivity, and reactivity due to its solubility. The gelation of FCP can be carried out by chemical crosslinking, but the mechanical strength of FCP hydrogel is very low because of its intrinsically low molecular weight. Therefore, the mechanical properties of FCP gel should be improved for its wider application as a biomaterial. In this study, we investigated the mechanical properties of M-FCP gel in the context of understanding the influence of chitin nanofibers (CHNFs) on FCP hydrogels. FCP with a number average molecular weight (M_n) of ca. 5000 was reacted with glycidyl methacrylate (GMA) and used for the preparation of photocrosslinked hydrogels. Subsequently, composite hydrogels of met

SUBMITTER: Yano S 

PROVIDER: S-EPMC9920125 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature