In Vitro Binding Effects of the Ecdysone Receptor-Binding Domain and PonA in Plutella xylostella.

ABSTRACT: Both insect ecdysone receptors and ultraspiracle belong to the nuclear receptor family. They form a nanoscale self-assembling complex with ecdysteroids in cells, transit into the nucleus, bind with genes to initiate transcription, and perform specific biological functions to regulate the molting, metamorphosis, and growth processes of insects. Therefore, this complex is an important target for the development of eco-friendly insecticides. The diamondback moth (Plutella xylostella) is a devastating pest of cruciferous vegetable crops, wreaking havoc worldwide and causing severe economic losses, and this pest has developed resistance to most chemical insecticides. In this study, highly pure EcR and USP functional domains were obtained by constructing a prokaryotic expression system fo

SUBMITTER: Feng Y 

PROVIDER: S-EPMC9920912 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature