The cortical regions and white matter tracts underlying auditory comprehension in patients with primary brain tumor.

ABSTRACT: The comprehension of spoken language is one of the most essential language functions in humans. However, the neurological underpinnings of auditory comprehension remain under debate. Here we used multi-modal neuroimaging analyses on a group of patients with low-grade gliomas to localize cortical regions and white matter tracts responsible for auditory language comprehension. Region-of-interests and voxel-level whole-brain analyses showed that cortical areas in the posterior temporal lobe are crucial for language comprehension. The fiber integrity assessed with diffusion tensor imaging of the arcuate fasciculus and the inferior longitudinal fasciculus was strongly correlated with both auditory comprehension and the grey matter volume of the inferior temporal and middle temporal gyri. Togeth

SUBMITTER: Zhang J 

PROVIDER: S-EPMC9921237 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature