Dataset Information

Effects of Substituents on the Photophysical/Photobiological Properties of Mono-Substituted Corroles.

ABSTRACT: The trans-A₂B-corrole series was prepared starting with 5-(pentafluorophenyl)dipyrromethene, which was then reacted with respective aryl-substituted aldehyde by Gryko synthesis. It was further characterized by HRMS and electrochemical methods. In addition, we investigated experimental photophysical properties (absorption, emission by steady-state and time-resolved fluorescence) in several solvents and TDDFT calculations, aggregation, photostability and reactive oxygen species generation (ROS), which are relevant when selecting photosensitizers used in photodynamic therapy and many other photo-applications. In addition, we also evaluated the biomolecule-binding properties with CT-DNA and HSA by spectroscopy, viscometry and molecular docking calculations assays.

SUBMITTER: de Souza VB

PROVIDER: S-EPMC9921392 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature

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Effects of Substituents on the Photophysical/Photobiological Properties of Mono-Substituted Corroles.

de Souza Vitória Barbosa VB da Rocha Vinícius N VN Piquini Paulo Cesar PC Chaves Otávio Augusto OA Iglesias Bernardo A BA

Molecules (Basel, Switzerland) 20230201 3

The <i>trans</i>-A<sub>2</sub>B-corrole series was prepared starting with 5-(pentafluorophenyl)dipyrromethene, which was then reacted with respective aryl-substituted aldehyde by Gryko synthesis. It was further characterized by HRMS and electrochemical methods. In addition, we investigated experimental photophysical properties (absorption, emission by steady-state and time-resolved fluorescence) in several solvents and TDDFT calculations, aggregation, photostability and reactive oxygen species g ...[more]

PMID: 36771053

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Dataset Information

Effects of Substituents on the Photophysical/Photobiological Properties of Mono-Substituted Corroles.

Publications

Effects of Substituents on the Photophysical/Photobiological Properties of Mono-Substituted Corroles.

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