Microfluidic Fabrication of Gadolinium-Doped Hydroxyapatite for Theragnostic Applications.

ABSTRACT: Among the several possible uses of nanoparticulated systems in biomedicine, their potential as theragnostic agents has received significant interest in recent times. In this work, we have taken advantage of the medical applications of Gadolinium as a contrast agent with the versatility and huge array of possibilities that microfluidics can help to create doped Hydroxyapatite nanoparticles with magnetic properties in an efficient and functional way. First, with the help of Computational Fluid Dynamics (CFD), we performed a complete and precise study of all the elements and phases of our device to guarantee that our microfluidic system worked in the laminar regime and was not affected by the presence of nanoparticles through the flow requisite that is essential to guarantee homogeneous diffu

SUBMITTER: Somoza M 

PROVIDER: S-EPMC9921701 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature