Assessment of transmitral and left atrial appendage flow rate from cardiac 4D-CT.

ABSTRACT:

Background

Cardiac time-resolved CT (4D-CT) acquisitions provide high quality anatomical images of the heart. However, some cardiac diseases require assessment of blood flow in the heart. Diastolic dysfunction, for instance, is diagnosed by measuring the flow through the mitral valve (MV), while in atrial fibrillation, the flow through the left atrial appendage (LAA) indicates the risk for thrombus formation. Accurate validated techniques to extract this information from 4D-CT have been lacking, however.

Methods

To measure the flow rate though the MV and the LAA from 4D-CT, we developed a motion tracking algorithm that performs a nonrigid deformation of the surface separating the blood pool from the myocardium. To improve the tracking of the LAA, this region was deformed sep

SUBMITTER: Back S 

PROVIDER: S-EPMC9922288 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature