DISCO+QR: rooting species trees in the presence of GDL and ILS.

ABSTRACT:

Motivation

Genes evolve under processes such as gene duplication and loss (GDL), so that gene family trees are multi-copy, as well as incomplete lineage sorting (ILS); both processes produce gene trees that differ from the species tree. The estimation of species trees from sets of gene family trees is challenging, and the estimation of rooted species trees presents additional analytical challenges. Two of the methods developed for this problem are STRIDE, which roots species trees by considering GDL events, and Quintet Rooting (QR), which roots species trees by considering ILS.

Results

We present DISCO+QR, a new approach to rooting species trees that first uses DISCO to address GDL and then uses QR to perform rooting in the presence of ILS. DISCO+QR operates by taking the in

SUBMITTER: Willson J 

PROVIDER: S-EPMC9923442 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature