Astrovirus Infection and Diarrhea in 8 Countries.

ABSTRACT:

Background and objectives

Astroviruses are important drivers of viral gastroenteritis but remain understudied in community settings and low- and middle-income countries. We present data from 8 countries with high prevalence of diarrhea and undernutrition to describe astrovirus epidemiology and assess evidence for protective immunity among children 0 to 2 years of age.

Methods

We used 25 898 surveillance stools and 7077 diarrheal stools contributed by 2082 children for enteropathogen testing, and longitudinal statistical analysis to describe incidence, risk factors, and protective immunity.

Results

Thirty-five percent of children experienced astrovirus infections. Prevalence in diarrheal stools was 5.6%, and severity exceeded all enteropathogens except rotavirus. Incid

SUBMITTER: Olortegui MP 

PROVIDER: S-EPMC9923568 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature