Ontology highlight
ABSTRACT:
SUBMITTER: Caban M
PROVIDER: S-EPMC9923667 | biostudies-literature | 2023 Feb
REPOSITORIES: biostudies-literature
Cabán Madelyn M Rodarte Justas V JV Bibby Madeleine M Gray Matthew D MD Taylor Justin J JJ Pancera Marie M Boonyaratanakornkit Jim J
Nature communications 20230213 1
Respiratory syncytial virus (RSV), human metapneumovirus (HMPV), and human parainfluenza virus types one (HPIV1) and three (HPIV3) can cause severe disease and death in immunocompromised patients, the elderly, and those with underlying lung disease. A protective monoclonal antibody exists for RSV, but clinical use is limited to high-risk infant populations. Hence, therapeutic options for these viruses in vulnerable patient populations are currently limited. Here, we present the discovery, in vit ...[more]